Pediatric Surgery
Disorders of Sexual Develpment with Dr. Kathy Graziano
An interactive discussion about disorders of sexual development between Todd Ponsky, MD and Kathy Graziano, MD.
Dr. Graziano is the director of the Reproductive Anomalies/Disorders of Sexual Development at Phoenix Children’s Hospital and is also the Director of the Arizona Fetal Care Network (AZFCN).
Intro track is adapted from "I dunno" by grapes, featuring J Lang, Morusque.
Artist URL: ccmixter.org/files/grapes/16626
License: creativecommons.org/licenses/by/3.0/
Sections
- Introduction (00:00)
- What is a disorder of sexual development? (02:23)
- Coordination of care (04:01)
- Initial approach (05:37)
- Role of the pediatric surgeon (06:17)
- Physical exam (07:46)
- Examination under anesthesia (09:48)
- Setting expectations (10:32)
- Differential diagnosis (11:15)
- KEY POINT – Ruling out CAH (12:01)
- Initial approach to ambiguous genitalia (12:44)
- Management of XX DSD (14:24)
- Role of ultrasound (15:56)
- Summary of XX DSD (17:11)
- Role of prenatal maternal steroids (18:00)
- “Normalizing” surgery (18:44)
- Differential for XY DSD (19:50)
- What is androgen insensitivity syndrome? (21:07)
- Urologic disorders mimicking DSD (23:04)
- Complete versus partial AIS (25:38)
- Mixed gonadal dysgenesis (26:49)
- Teenagers with DSD (30:01)
- Mayer-Rokitansky-Küster-Hauser syndrome (32:31)
- Evaluation and management of AIS (37:47)
- Role of biopsy (43:02)
- Gender assignment (43:39)
- Delayed gender assignment (44:27)
- Multidisciplinary DSD Clinic (49:00)
- Closing remarks (49:56)
- Contact info for Dr. Graziano (53:17)