Dr. Jaimie Nathan introduces the session, covering indications for total pancreatectomy with islet auto-transplantation (TPIAT), pre-TPIAT evaluation, pre- and post-operative management, and long-term follow-up. 
Dr. Joe Palermo presents a chronic pancreatitis case study to the panel. Panel members discuss topics of endoscopic retrograde cholangiopancreatography (ERCP), human genetics, and infectious disease.
Dr. Deborah Elder, pediatric endocrinologist, discusses endocrinology considerations, assessment of pancreatic endocrine reserve, beta-cell function pre-TPIAT, oral glucose tolerance (OGTT), mixed meal testing (MMT), and type 3C diabetes (pancreatogenic diabetes).
Dr. Kenneth R. Godschneider discusses preoperative pain management.